PEG5-Ms
Product Name : PEG5-MsCAS : 65883-12-7Formula : C9H20O7SMW: 272.3Description : PEG5-Ms is a PEG linker with a mesyl group and a hydroxyl group. Ethyl 2-formylthiazole-4-carboxylate Chemscene (4-Bromopyridin-2-yl)methanamine web The mesyl…
Pyrene-PEG5-alcohol
Product Name : Pyrene-PEG5-alcoholCAS : 1817735-44-6Formula : C27H31NO6MW: 465.6Description : DBCO-PEG-8-Val-Cit-PAB-PNP is a cleavable ADC linker. The Val-Cit linkers can be cleaved by Cathepsin B. The DBCO groups is commonly…
1,1,1-Trifluoroethyl-PEG4-azide
Product Name : 1,1,1-Trifluoroethyl-PEG4-azideCAS : 1817735-35-5Formula : C10H18F3N3O4MW: 301.3Description : 1,1,1-Trifluoroethyl-PEG4-azide is a crosslinker containing an azide group and a trifluoroethyl group. The azide group enables Click Chemistry. The hydrophilic…
1,1,1-Trifluoroethyl-PEG5-Propargyl
Product Name : 1,1,1-Trifluoroethyl-PEG5-PropargylCAS : 1817735-37-7Formula : C13H21F3O5MW: 314.3Description : 1,1,1-Trifluoroethyl-PEG5-Propargyl forms triazole linkage with azides via copper catalyzed azide-alkyne Click Chemistry. The trifluoroethyl group is reactive towards primary amine…
Methylamino-PEG5-azide
Product Name : Methylamino-PEG5-azideCAS : 2055046-24-5Formula : C13H28N4O5MW: 320.4Description : Methylamino-PEG5-azide is a PEG linker containing an azide group and a methylamino group. The azide group enables Click Chemistry. The…
Tetra(Cyanoethoxymethyl) Methane
Product Name : Tetra(Cyanoethoxymethyl) MethaneCAS : 2465-91-0Formula : C17H24N4O4MW: 348.4Description : Tetra(cyanoethoxymethyl) methane is an alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs. The nitrile…
Evealed that TBME and K2CO3 were optimal, delivering tertiary alcohol
Evealed that TBME and K2CO3 were optimal, providing tertiary alcohol 2b with 20:1 diastereoselection and 96:4 er (Table 1, entry 10). Efforts to further enhance stereoselectivity by introduction of steric…
He WT, whereas U5 snRNA cross-links to Prp8 at equivalent levels
He WT, whereas U5 snRNA cross-links to Prp8 at related levels in each strains. (f) Spliceosomal B complicated assembled in the U1 ?84?12 strain has comparable U1 snRNA level but…